2

Identification and targeting of a HES1‐YAP1‐CDKN1C functional interaction in fusion‐negative rhabdomyosarcoma
Rhabdomyosarcoma (RMS), a cancer characterized by features of skeletal muscle, is the most common soft-tissue sarcoma of childhood. …
Alexander R Kovach, Kristianne M Oristian, David G Kirsch, Rex C Bentley, Changde Cheng, Xiang Chen, Po‐Han Chen, Jen‐Tsan Ashley Chi, Corinne M Linardic
PDF DOI
Identification and targeting of a HES1‐YAP1‐CDKN1C functional interaction in fusion‐negative rhabdomyosarcoma
Molecular evolution and the decline of purifying selection with age
Life history theory predicts that the intensity of selection declines with age, and this trend should impact how genes expressed at …
C. Cheng, M. Kirkpatrick
PDF Cite Slides DOI
Molecular evolution and the decline of purifying selection with age
Predicting the evolution of sexual dimorphism in gene expression
Sexual dimorphism in gene expression is likely to be the underlying source of dimorphism in a variety of traits. Many analyses …
D. Houle, C. Cheng
PDF Cite DOI
Predicting the evolution of sexual dimorphism in gene expression
Predicting multivariate responses of sexual dimorphism to direct and indirect selection
Sexual dimorphism is often assumed to result from balancing the strength of antagonistic selection in favor of dimorphism against the …
C. Cheng, D. Houle
PDF Cite DOI
Predicting multivariate responses of sexual dimorphism to direct and indirect selection
Complex interactions between day length and diurnal patterns of gene expression drive photoperiodic responses in a perennial C4 grass
Photoperiod is a key environmental cue affecting flowering and biomass traits in plants. Key components of the photoperiodic flowering …
X. Weng, J. T. Lovell, S. L. Schwartz, C. Cheng, T. Haque, L. Zhang, S. Razzaque, T. E. Juenger
PDF Cite DOI
Complex interactions between day length and diurnal patterns of gene expression drive photoperiodic responses in a perennial C4 grass
Inversions are bigger on the X chromosome
In many insects, X-linked inversions fix at a higher rate and are much less polymorphic than autosomal inversions. Here, we report that …
C. Cheng, M. Kirkpatrick
PDF Cite Slides DOI
Inversions are bigger on the X chromosome
Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data
Single-cell RNA sequencing (scRNA-seq) is a powerful tool for characterizing the cell-to-cell variation and cellular dynamics in …
C. Cheng, J. Easton, C. Rosencrance, Y. Li, B. Ju, J. Williams, H. L. Mulder, Y. Pang, W. Chen, X. Chen
PDF Cite DOI
Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data
Metabolic signaling directs the reciprocal lineage decisions of alphabeta and gammadelta T cells
The interaction between extrinsic factors and intrinsic signal strength governs thymocyte development, but the mechanisms linking them …
K. Yang, D. B. Blanco, X. Chen, P. Dash, G. Neale, C. Rosencrance, J. Easton, W. Chen, C. Cheng, Y. Dhungana, A. Kc, W. Awad, X. J. Guo, P. G. Thomas, H. Chi
PDF Cite DOI
Metabolic signaling directs the reciprocal lineage decisions of alphabeta and gammadelta T cells
Sex differences in recombination in sticklebacks
Recombination often differs markedly between males and females. Here we present the first analysis of sex-specific recombination in …
J. M. Sardell, C. Cheng, A. J. Dagilis, A. Ishikawa, J. Kitano, C. L. Peichel, M. Kirkpatrick
PDF Cite DOI
Sex differences in recombination in sticklebacks
Systems genetic analysis of inversion polymorphisms in the malaria mosquito Anopheles gambiae
Inversion polymorphisms in the African malaria vector Anopheles gambiae segregate along climatic gradients of aridity. Despite indirect …
C. Cheng, J. C. Tan, M. W. Hahn, N. J. Besansky
PDF Cite DOI
Systems genetic analysis of inversion polymorphisms in the malaria mosquito Anopheles gambiae